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The Nikkei 225 index closed up 1.21% at 39,849.14.Market News: The Slovak Prime Minister said that Slovakia supports the normalization of relations between Russia and western countries and opposes the emergence of a new iron curtain in Europe. The Slovak Prime Minister emphasized that all conflicts will be finally resolved through negotiations.Network Information Office: The Network Security Standards Committee should speed up the development and release of standards such as "Identification Method of Synthetic Content Generated by Artificial Intelligence" and strengthen the research on relevant network security standards such as intelligent networked vehicles. The second "Standards Week" of the National Network Security Standardization Technical Committee in 2024 was held in Haikou City, Hainan Province from December 8 th to 11 th. Wang Jingtao, deputy director of the National Network Information Office, pointed out that standing at a new starting point and a new journey, the Network Security Standards Committee should do a solid job in network security standardization. First, it is necessary to build a national network security defense system supported by standards, and promote the release and implementation of standards such as the boundary determination method of key information infrastructure, the index system of security protection capability, the alarm information format of network security products, and the asset information format as soon as possible, and accelerate the formation of systematic defense capabilities. Second, it is necessary to use standards to help data security governance and supervision, speed up the development of standards such as data classification and classification protection requirements and compliance audit of personal information protection, and ensure the safe and orderly flow of data. Third, it is necessary to lead the safe and orderly development of new technologies and applications such as artificial intelligence with standards and norms, accelerate the development and release of standards such as "Identification Method of Synthetic Content Generated by Artificial Intelligence", and strengthen the research on relevant network security standards such as intelligent networked vehicles and autonomous driving, effectively escorting the safe development of emerging future industries. Fourth, we should use standards to boost the international influence of China's cybersecurity, continue to push China's cybersecurity standards "going global", do our best to run the SC27 international conference in the second half of 2025, and strive to achieve a double harvest of conference organization and conference technical achievements.

In the latest centralized purchase of sitagliptin tablets, the price dropped to less than 20 cents per tablet, with a drop of over 90%. The reporter learned at the scene of the tenth batch of drug centralized purchase that more than 30 companies bid for sitagliptin, which is known as the largest variety in this centralized purchase, including Huahai Pharmaceutical, Kelun Pharmaceutical, Zhengda Tianqing, tonghua dongbao, Zhejiang Pharmaceutical, Jiudian Pharmaceutical, Shiyao Ouyi, Chenxin Pharmaceutical and many other companies. Judging from the bidding results, the lowest bid price among enterprises has dropped below 0.2 yuan per piece, which is more than 90% lower than the limit price. Statistics show that in 2023, the sales of this product in the terminals of public medical institutions in China exceeded 2 billion yuan, and the sales of Merck, the original research manufacturer, accounted for more than 90%, so there is a large room for the replacement of generic drugs. The quotation of Meradong in this collection is about 7.37 yuan per piece. (science and technology innovation board Daily)The latest collection price of the heavy anticancer star drug Regofibril has dropped to a minimum of more than 4 yuan per tablet. The reporter learned at the scene of the tenth batch of drug collection that the anti-tumor drug Regofibril tablets with annual sales of more than 1 billion yuan have been auctioned by this collection, and the price has almost dropped to between 4 yuan and 6 yuan, which is 90% lower than the price limit. Nanjing Zhengda Tianqing is expected to win the bid in the first round of quotation. Regofibril can treat colorectal cancer, liver cancer and other cancers. Its original research manufacturer is Bayer, which occupies almost all the market share in China. The price of this collection is about 172 yuan per tablet. (science and technology innovation board Daily)On December 12, the average price of pork in the national agricultural products wholesale market was 23.14 yuan/kg, which was the same as yesterday. According to the monitoring of the Ministry of Agriculture and Rural Affairs, the "200 Index of Agricultural Products Wholesale Price" was 121.01 on December 12, up 0.07 points from yesterday, and the wholesale price index of "vegetable basket" products was 122.15, up 0.08 points from yesterday. As of 14:00 today, the average price of pork in the national agricultural products wholesale market was 23.14 yuan/kg, which was the same as yesterday; Beef is 60.10 yuan/kg, down 0.4% from yesterday; Mutton 59.19 yuan/kg, up 0.2% from yesterday; Eggs are 10.19 yuan/kg, up 0.2% from yesterday; White striped chicken was 17.74 yuan/kg, down 0.5% from yesterday. The average price of 28 kinds of vegetables monitored is 5.02 yuan/kg, up 0.2% from yesterday; The average price of six kinds of fruits monitored is 7.15 yuan/kg, down 0.4% from yesterday. Crucian carp 19.28 yuan/kg, down 1.6% from yesterday; Carp 14.30 yuan/kg, down 0.6% from yesterday; Silver carp 10.10 yuan/kg, down 3.3% from yesterday; Hairtail is 41.11 yuan/kg, up 1.3% from yesterday.

Hong Kong Stock Exchange: Before the end of 2025, the system will be technically compatible with the T+1 settlement cycle. The Hong Kong Stock Exchange announced on December 12 that it will launch a plan to improve the post-trading service of the stock spot market. Starting from mid-2025, the Hong Kong Stock Exchange will gradually introduce new post-trading functions on its OCP. The new functions include automatic report downloading and information exchange, real-time transmission and processing of transaction data, related positions and reference data, and real-time delivery instruction pairing. As part of the whole platform upgrade plan, HKEx will ensure that its system is technically compatible with the T+1 settlement cycle by the end of 2025. However, what kind of settlement cycle will be adopted in Hong Kong in the future will be decided after market discussion.Foreign media: The Italian neo-Nazi organization planned to assassinate the Prime Minister, which was foiled by the police. According to the British "Daily Telegraph" reported on the 11th, an Italian neo-Nazi organization was accused of planning to assassinate Prime Minister Giorgiya meloni and World Economic Forum President klaus schwab, and the assassination plot was foiled by the police. The report quoted local media as saying that last week, the police carried out raids in various parts of Italy, arrested 12 people suspected of participating in the far-right organization, and seized a batch of knives, military clothing and propaganda materials. The organization originally called itself "Wolf Division" and later renamed it "New Dawn Division". The police said that some suspects arrested called meloni a "fascist who persecuted fascists" and had planned to assassinate her since 2023. (Global Times)US Treasury Secretary Yellen: The oil market is well supplied and the price is relatively low. US Treasury Secretary Yellen said that the oil market is well supplied and the price is relatively low. Russia has invested a lot of money in its fleet to avoid the western oil price cap sanctions.